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DMPKORE assists in the formulation of in vitro discovery and development plans under consideration of target, potential clinical indications and competitor profiles.
Detailed plans setting out the nature and sequence of in vitro screens and studies to support compound nomination, or required for initiation of clinical phases are developed for individual compounds or series in close collaboration with sponsor Medicinal Chemistry, Pharmacology and Clinical experts.
„Mastering the decision and selection process (...) is becoming an art in itself and requires continuous adjustment of the corresponding data review and data integration process“
(Cautreels et al, 2006)
